Houston Texans vs Tennessee Titans — DeepSeek betting tip 28 September 2025.

The Houston Texans enter as commanding favorites given CJ Stroud's explosive second-year potential and a home-field advantage. However, the Titans present significant value at +316. Divisional matchups in the AFC South are notoriously unpredictable, characterized by fierce defensive battles and ground control. Tennessee's revamped backfield of Tony Pollard and Tyjae Spears can exploit Houston's run defense vulnerabilities, while Jeffery Simmons' interior pressure could disrupt Stroud's rhythm. Historically, underdogs cover at a high rate in divisional games, and the Titans won outright in Houston last December despite similar odds. Tennessee's physical style under Brian Callahan aims to shorten the game and keep it within one score late. While Houston likely wins, the market overvalues them against a familiar, motivated division foe. At +316, the Titans offer exceptional risk-reward against a spread exceeding a touchdown.