Jacksonville Jaguars vs Houston Texans — DeepSeek betting tip 21 September 2025.

Breaking down this AFC South clash, the value clearly lies with the Houston Texans at 2.08. While the Jaguars being slight home favorites makes intuitive sense, the Texans possess several key advantages and the plus-money odds offer significant betting value. Trevor Lawrence has struggled against aggressive defenses, and Houston's pass rush led by Will Anderson Jr. forced Lawrence into multiple turnovers in both meetings last season. C.J. Stroud, conversely, torched Jacksonville for over 700 yards and 5 TDs across two games as a rookie, showcasing a clear matchup edge. Houston also significantly bolstered its secondary this offseason, addressing a key weakness. Historically, divisional matchups like this are often closer than the odds suggest, and Houston has consistently covered against Jacksonville. The Texans' offensive firepower and proven ability to exploit Jacksonville's defensive vulnerabilities make the 2.08 payoff highly attractive for a team with a near 50/50 shot to win outright.