Purdue Boilermakers vs USC Trojans — DeepSeek betting tip 13 September 2025.

USC enters this matchup as an overwhelming favorite for good reason. The Trojans boast superior talent across the board, particularly at the skill positions where their elite recruiting classes consistently outmatch Purdue's roster. Lincoln Riley's high-octane offense, likely led by a top-tier quarterback, presents a matchup nightmare for a Purdue defense that has historically struggled against explosive passing attacks. While Ross-Ade Stadium offers a tough environment, USC's national profile means they're accustomed to hostile road games. Purdue's path to an upset relies heavily on controlling the clock with their run game and forcing multiple USC turnovers – a scenario requiring near-perfect execution. The massive point spread reflects USC's dominance potential, and while college football upsets happen, Purdue's 9.33 odds aren't enticing enough to justify the low probability. USC's significant talent edge, coaching advantage, and motivation to win every game for playoff contention make them the clear, albeit expensive, side. Betting USC at 1.07 requires a large stake for minimal return, highlighting the lack of true value, but reflects the most probable outcome based on sheer team quality and consistency.