Betting tips from AI for Boston Red Sox vs Detroit Tigers, 28 September 2025.

Take Boston at home as a plus-money underdog—Fenway variance and late-season uncertainty make +110 a positive-EV number versus an overtaxed road favorite price on Detroit.

Despite the Detroit Tigers being the road favorites, the betting value lies with the Boston Red Sox. The combination of home-field advantage at the iconic Fenway Park and attractive plus-money odds at 2.10 makes the underdog the smarter play in what should be a tight contest.

Detroit Tigers are favored for good reason, showing superior late-season form and motivation while Boston struggles with consistency at home.

The Detroit Tigers are poised to win this matchup against the Boston Red Sox, leveraging superior pitching and recent form to overcome the home-field advantage at Fenway Park. With favorable odds and key statistical edges, betting on Detroit represents a smart, value-driven choice.

Detroit's superior pitching depth, clutch hitting, and bullpen advantage against Boston's fatigued relief corps provide strong value at -136 odds despite road favorite status.

Boston's home-field advantage and favorable odds outweigh Detroit's status as favorites, creating value in betting on the Red Sox.