Betting tips from AI for Cincinnati Bengals vs Arizona Cardinals, 28 December 2025.

This is a clash of narratives: Squawka and efficiency metrics lean heavily toward the Bengals, and the market reflects that with the home side installed as a strong favorite at 1.30. Cincinnati’s explosive 45-21 road performance last week shows the offense can light it up, and historical edge (34-20 last meeting) plus per-play dominance make them the safer moneyline play.

Arizona has upset potential — SportsGambler even pegs a 30-28 shock — but their three-game road skid and 20.9 ppg on the road make them unreliable. The value here is backing the more consistent attack and home advantage: pick Cincinnati over long odds of 3.76.

This NFL clash between the Cincinnati Bengals and Arizona Cardinals presents an intriguing betting scenario. While the Bengals are heavy favorites at 1.30, their recent four-game home losing streak might give bettors pause. However, their dominant 45-21 road thrashing of Miami last week, racking up 407 yards and six touchdowns, showcased their offensive firepower and ability to perform at a high level.

The Cardinals, conversely, are mired in a three-game road skid and have a dismal 2-8 record in their last 10 away outings, averaging a mere 20.9 points while leaking 25.3 per game. This paints a grim picture for their chances against a Bengals team eager to break their home slump. While some projections like SportsGambler predict a nail-biter or even an upset, Squawka analysts are "all-in on Cincinnati dominating outright" due to their superior home-field edge and efficiency. Given Arizona's significant road struggles and Cincinnati's recent offensive explosion, the Bengals are poised to secure a much-needed home victory. The odds reflect the talent disparity and the Cardinals' current form.

The Bengals enter this NFL showdown at Paycor Stadium as heavy favorites at 1.30, but their four straight home losses cast a shadow over that status, even after a commanding 45-21 road win over Miami last week where they racked up 407 yards and six TDs. The Cardinals, meanwhile, are stumbling through a three-game road skid and a dismal 2-8 record in their last 10 away games, averaging just 20.9 points while surrendering 25.3 per contest. History is split: Cincinnati dominated 34-20 in their most recent clash, but Arizona exacted revenge 36-23 the time before at this very venue.

Expert takes add intrigue—SportsGambler sees a gritty Cardinals upset in a 30-28 nail-biter, covering the +7 spread, while a 790 Louisville model predicts a 27-24 Bengals squeaker but still favors Arizona to keep it tight. Squawka, however, is locked on Cincinnati's moneyline triumph, highlighting their superior home-field edge and per-play efficiency against a floundering foe.

Weighing it all, the Bengals' talent and bounce-back potential outweigh the Cardinals' road woes. Expect Cincinnati to grind out a victory, covering the spread in a high-scoring affair that rewards the favorites. For bettors eyeing value, the 1.30 line offers a safe play to build the bankroll steadily.

The Bengals are heavy favorites at 1.30, and the data supports their edge. Despite a puzzling four-game home losing streak, they exploded offensively last week with 407 yards and six TDs in Miami. The Cardinals are mired in a 2-8 road slump, averaging just 20.9 points while allowing 25.3. While some models project a close game, Cincinnati's superior per-play efficiency and home-field advantage, as noted by analysts, should prevail. Recent history is split, but the Bengals' offensive firepower is the deciding factor against Arizona's struggling road form.

This matchup between the Cincinnati Bengals and Arizona Cardinals presents an intriguing clash of narratives, with betting value worth exploring. The Bengals enter as heavy favorites at 1.30, reflecting their perceived dominance on paper. However, recent trends suggest cracks in their armor. Despite a dominant 45-21 road win over Miami last week, the Bengals have lost four consecutive home games, raising questions about their ability to capitalize on their home-field advantage.

On the flip side, the Cardinals, though struggling with a 2-8 record in their last 10 road games, have shown glimpses of resilience. Their average scoring output of 20.9 points per game may not dazzle, but they’ve proven capable of keeping games close. Projections like the one from 790 Louisville anticipate a high-scoring affair, backing Arizona to cover the +7 spread. SportsGambler experts even foresee a narrow upset, predicting a 30-28 Cardinals victory.

The historical context adds another layer of intrigue. While the Bengals dominated their last meeting 34-20, the Cardinals exacted revenge in their prior Paycor Stadium clash, winning 36-23. This back-and-forth dynamic hints at Arizona’s potential to rise to the occasion once again.

With the Cardinals offering enticing odds at 3.76, the risk-reward balance tilts favorably toward backing the underdog. Given the Bengals’ shaky home form and Arizona’s knack for staying competitive, the Cardinals are primed to defy expectations.