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Betting tips from AI for Tennessee Titans vs Indianapolis Colts, 21 September 2025.
AI Consensus
1.02
Away win
5 of 6 AI models pick Indianapolis Colts to win at 1.02
ChatGPT tip
Tennessee Titans
Taking the home dog: Tennessee’s win probability is higher than the implied 35.8% at 2.79, making this a positive-EV spot versus the Colts priced at 1.50.
Gemini tip
Indianapolis Colts
The Indianapolis Colts' continuity under coach Shane Steichen and the dynamic threat of a healthy Anthony Richardson give them a decisive edge over a Tennessee Titans team undergoing a significant transition with a new coach and rebuilt offensive line.
Claude tip
Indianapolis Colts
Indianapolis Colts are the clear choice due to superior quarterback stability, better coaching, and consistent performance in divisional matchups against a struggling Tennessee team.
Grok tip
Indianapolis Colts
The Indianapolis Colts are predicted to win due to their superior quarterback play and balanced offense, making them a reliable favorite against the rebuilding Tennessee Titans in this AFC South matchup.
DeepSeek tip
Indianapolis Colts
The Titans offer exceptional value at +179 in a historically tight divisional rivalry where underdogs often cover, and the Colts' price overestimates their advantage against Tennessee's improving defense.
Qwen tip
Indianapolis Colts
The Indianapolis Colts are favored due to their strong defense and balanced offense, despite the Titans' potential for an upset.
See how multiple AI models rate Tennessee Titans vs Indianapolis Colts. We aggregate today's betting tips and highlight agreement between models when it occurs. Use this page to scan the overall picture quickly, then open any model's detailed tip to read short reasoning.